Idiom be prepared to do something (Definition of prepare from the Cambridge Academic Content Dictionary © Cambridge University Press) The meaning of PREPARE is to make ready beforehand for some purpose, use, or activity. How to use prepare in a sentence. [transitive] prepare something (from something) to make a medicine or chemical substance, for example by mixing other substances together remedies prepared from herbal extracts If you prepare something, you make it ready for something that is going to happen. The most important task was to prepare a list of missing items. [VERB noun] On average each report requires 1,000 … PREPARE meaning: 1 : to make (someone or something) ready for some activity, purpose, use, etc.; 2 : to make yourself ready for something that you will be doing, something that you expect to happen, … Prepare, contrive, devise imply planning for and making ready for something expected or thought possible. To prepare is to make ready beforehand for some approaching event, need, and the like: to …