WildCucumberControl. The best way to controlwildcucumber vines is to hoe or pull the plants as soon as you notice them in spring. ControlWildcucumber and burcucumber seeds germinate throughout the summer especially after rain, which makes periodic scouting and removal crucial for control. Learn how to controlWildCucumber (preemergence) with these easy to use products! Biological control: Use specific insects or goats to feed on the wildcucumber. Take care to monitor the process to ensure the control agents do not become pests themselves. WildCucumber Vine - Learn About WildCucumberControl | Cucumber seeds, Plant problems, Tiny white flowers. Green Seed Pods In Nature. Hi, I'm new to the site, I signed up to post a question on the control of what I've been told is wildcucumber. The best way to controlwildcucumber vines is to hoe or pull the plants as soon as you notice them in spring. If you don't notice them early in the season, you can mow the vines repeatedly... If you have wildcucumber vine on your property and want to attempt to control it, you can cut it off near the ground and the rest will die. Don’t spray 2,4-D or any other herbicide on the vines because anything that would control the wildcucumber can damage or even kill the trees that wildcucumber is vining up on. If you want to controlwildcucumber, just pull it out of the ground or cut the stem off near the bottom of the vine. Since it is an annual it will die with a good frost too.